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Autism

NIH grant to support research into connections between autism, sensory hypersensitivity

Supported by a $2 million grant from the National Institutes of Health, the Auerbach Lab will examine how different genes associated with autism spectrum disorders may similarly impact our brain’s neurons, resulting in heightened sensitivity to sounds.  Autism spectrum disorders are genetically...

Protein p53 regulates learning, memory, sociability in mice

University of Illinois researchers have established the protein p53 as critical for regulating sociability, repetitive behavior, and hippocampus-related learning and memory in mice, illuminating the relationship between the protein-coding gene TP53 and neurodevelopmental and psychiatric disorders...

Research illuminates balancing act for protein linked to Fragile X Syndrome and Alzheimer's disease

A new study by researchers at the University of Illinois Urbana-Champaign suggests the overexpression of a particular gene could serve as a risk factor for Alzheimer’s disease. Their findings could also lead to better understandings of the links between Alzheimer’s disease, Fragile X Syndrome, and...

Meet MCB: Professor Nien-Pei Tsai

Dr. Tsai’s lab focuses on understanding the molecular mechanisms underlying neuronal excitability imbalance in neurological and psychiatric disorders including epilepsy and autism.

Study reveals neuronal response following chronic activation of an epilepsy- and autism-linked receptor

Group 1 metabotropic glutamate receptors (Gp1 mGluRs) are essential for neuroplasticity, neurodevelopment and cognition, but chronically active Gp1 mGluRs has been linked to many pathologic conditions including epilepsy and autism spectrum disorders. To characterize the effects of chronically...