New research from the K.V. Prasanth lab, in collaboration with scientists across the University of Illinois and other institutions, has revealed that gene positioning near nuclear speckles — key nuclear domains that promote gene expression — along with the mechanistic functions of the non-coding...
Researchers from the University of Illinois Urbana-Champaign are piecing together how cancer-emergent non-coding RNAs, or ncRNAs, contribute to disease-related cell phenotypes. The Van Bortle lab has focused extensively on RNA polymerase III (Pol III) —...
University of Illinois researcher Erik Nelson and members of his lab have made an important discovery about the relationship between cholesterol and breast cancer progression with crucial implications for breast cancer therapeutics....
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report. The protein, FGD3,...
University of Illinois researchers have successfully treated a common type of colorectal cancer tumor with a cholesterol inhibitor drug, demonstrating a promising treatment for the disease in animal experiments.The study,...
School of Molecular & Cellular Biology professor Lin-Feng Chen has published new research reporting an important factor driving chemoresistance for patients with colorectal cancer. The research was published in the journal...
