Breast cancer is categorized into three major subtypes: hormone receptor-positive, HER2-positive, and triple-negative. Although there are targeted therapeutic approaches for the first two, there are limited options for triple negative-breast cancer patients. In a new study, researchers have...
University of Illinois biochemistry professor Kai Zhang and collaborators developed a technique using light to regulate mitochondria, the energy-producing powerhouses inside cells. The technique could address mitochondrial diseases and cancer.
New research from Supriya Prasanth’s lab at the University of Illinois provides tremendous insight into the role of the smallest subunit of the human ORC, Orc6. Although the ORC is conserved in all eukaryotes, Orc6 is the most evolutionarily diverged. In a recent study published in PNAS, the...
Kalsotra’s research has focused on RNA, the workhorse cousin of DNA, which makes up the genetic instructions for living things. RNA is often viewed as important for messaging and other functions, taking DNA’s code and transporting it to and carrying out functions in cells. It’s often taken a back...
Thirteen years ago, when Lin-Feng Chen joined the Department of Biochemistry, he had his sights set on a specific protein that could both contribute to the growth of cancer and be a major factor in boosting the body’s immune system.
David Kranz, the Phillip A. Sharp Professor of Biochemistry in the School of Molecular and Cellular Biology, has been involved in T-cell research since working as a postdoctoral researcher at the Massachusetts Institute of Technology, involved in early discoveries about how T-cells might be used to...
Several MCB faculty members are part of an exciting new campus unit known as The Cancer Center at Illinois. The Center is an interdisciplinary collaborative hub with more than 100 faculty members from departments ranging from kinesiology, human development and nutrition to electrical and computer...
Researchers at the University of Illinois Urbana-Champaign and Stanford University School of Medicine have identified a link between RNA polymerase III subunit composition and transcription, an advancement that has potential implications for future cancer research. Their findings were published in...
Hashni Epa Vidana Gamage is a PhD student in the School of Molecular and Cellular Biology at the University of Illinois Urbana-Champaign. In our latest "Meet MCB" video, Hashni shares what it means to her to be a part of a lab researching ways to improve breast cancer treatment.
Urbana, Ill. – A new study by Cancer Center at Illinois Education Program Leader, Zeynep Madak-Erdogan and her team, have found a new mechanism of endocrine resistance in breast cancers metastasized to the liver.