Building upon decades of research, scientists at the University of Illinois have determined Escherichia coli (E. coli) induces DNA repair enzymes to protect itself from low-grade hydrogen peroxide (H2O2) stress. Their collective findings, published recently in Molecular Microbiology, suggest the...

Professor Andrei Kuzminov and PhD student Pooja Agashe from the Department of Microbiology at the University of Illinois Urbana-Champaign recently explored hydrogen peroxide’s synergistic effects with nitric oxide (NO).

The latest paper by the Kuzminov lab investigates the mechanism of thymineless death, which is a common mode of action of anti-cancer and anti-bacterial drugs. The findings were published in a paper titled "Sources of thymidine and analogs fueling futile damage-repair cycles and ss-gap accumulation...

The latest paper by the Kuzminov lab describes the development of a highly sensitive method to probe the nature of DNA replication in E. coli. The findings were published in a paper titled “Near-continuously synthesized leading strands in Escherichia coli are broken by ribonucleotide excision” in...

Discovery provides deeper insight into DNA and the fight against cancer.