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Regulation of Gene Expression

Belmont Lab offers new insights on nuclear speckles, improved mapping method

In a new publication, University of Illinois PhD graduate Liguo Zhang of the Belmont laboratory and colleagues introduce an improved version of TSA-seq and use it to demonstrate how changes in gene association with nuclear speckles correlate with changes in gene expression.

Cronan lab uncovers mechanism for synthesis of pimelate moiety, the biotin precursor

Professor John. E. Cronan, Microbiology Alumni Professor and professor of biochemistry at the University of Illinois, is a leading researcher and innovator in the field of lipid metabolism. His recent work focuses on the synthesis of biotin and its building blocks across different species of...

Researchers uncover the role of a noncoding RNA in cell proliferation

Kannanganattu V. Prasanth, professor of cell and developmental biology, and members of his lab investigate the regulation of gene expression and RNA biology with a focus on cancer. In a new article published in eLife, “The S-phase-induced lncRNA promotes cell proliferation by controlling YAP1/Hippo...

Brian Freeman named a fellow of Cell Stress Society International

Congratulations to Brian Freeman, professor of cell and developmental biology at the University of Illinois who has been selected as a fellow of the Cell Stress Society International.

Nuclear speckle contact amplifies gene expression

Recent work from the Laboratory in Cell and Developmental Biology was featured in the Journal of Cell Biology.