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Regulation of Gene Expression

New faculty members begin teaching and research at U of I

The College of LAS is welcoming 38 new professors for the 2022-23 academic year. Their new positions range from clinical professors to assistant professors and an endowed position in more than 20 academic units, ranging from African American studies to economics, philosophy, statistics, and several...

Researchers determine Pol III “identity” as important regulatory mechanism and likely disease factor in cancer

Researchers at the University of Illinois Urbana-Champaign and Stanford University School of Medicine have identified a link between RNA polymerase III subunit composition and transcription, an advancement that has potential implications for future cancer research. Their findings were published in...

Decoding the molecular clock that controls neurogenesis in visual center of Drosophila

The nervous system is made up of diverse cells that arise from progenitors in a specific time-dependent pattern. In a new study, published in Nature Communications, researchers have uncovered the molecular players involved and how the timing is controlled.

Meet MCB: Temirlan Shilikbay, cell & developmental biology PhD student

The School of MCB is proud to highlight our graduate students, including Temirlan Shilikbay, now in his third year at the University of Illinois Urbana-Champaign. He is a PhD candidate in professor Stephanie Ceman's lab in the Department of Cell and Developmental Biology. The lab's goal is to study...

Meet MCB: Professor Brian Freeman brings molecular chaperone expertise to Illinois

Brian Freeman, a professor of cell and developmental biology and Cancer Center at Illinois scientist, has focused his research on the study of molecular chaperones (MCs) since the beginning of his career as a graduate student when chaperones were thought to have no medicinal purpose. Now, the...

Researchers find new control mechanism for sugar metabolism in gut microbes

In a new University of Illinois study, researchers found that genes encoding a previously unstudied family of RBPs are highly expressed in many Bacteroides species. They also demonstrated that mutants of the prevalent human gut bacteria Bacteroides thetaiotaomicron that lacked RBPs exhibited...

Researchers identify mechanisms of controlling regeneration for two chromatin-remodeling complexes of Drosophila

Rachel Smith-Bolton, a professor of cell and developmental biology at the University of Illinois, leads an exciting research program on tissue regeneration. Her recent work uses Drosophila as a model to explore the effects of different chromatin modifiers on initiating, spatially controlling, and...

Researchers characterize the function of PaeA, a protein involved in Salmonella virulence

The regulation of polyamines is essential for the physiological function of organisms. Simplistically, polyamines are organic cations that interact with RNA, including ribosomes and translational machinery. Both the lack of and an excess of polyamines confer lethal phenotypes, though the molecular...

Belmont Lab offers new insights on nuclear speckles, improved mapping method

In a new publication, University of Illinois PhD graduate Liguo Zhang of the Belmont laboratory and colleagues introduce an improved version of TSA-seq and use it to demonstrate how changes in gene association with nuclear speckles correlate with changes in gene expression.

Cronan lab uncovers mechanism for synthesis of pimelate moiety, the biotin precursor

Professor John. E. Cronan, Microbiology Alumni Professor and professor of biochemistry at the University of Illinois, is a leading researcher and innovator in the field of lipid metabolism. His recent work focuses on the synthesis of biotin and its building blocks across different species of...