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RNA Biology

Possible genetic basis and mouse model found for severe nonalcoholic fatty liver disease

The SRSF1 gene acts as a guardian against DNA damage in the liver, School of MCB researchers found. When it is missing or inactivated, severe nonalcoholic fatty liver disease symptoms develop.

New faculty members begin teaching and research at U of I

The College of LAS is welcoming 38 new professors for the 2022-23 academic year. Their new positions range from clinical professors to assistant professors and an endowed position in more than 20 academic units, ranging from African American studies to economics, philosophy, statistics, and several...

Exploring RNA’s Binding Role in Liver Disease and Cancer

Kalsotra’s research has focused on RNA, the workhorse cousin of DNA, which makes up the genetic instructions for living things. RNA is often viewed as important for messaging and other functions, taking DNA’s code and transporting it to and carrying out functions in cells. It’s often taken a back...

Researchers determine Pol III “identity” as important regulatory mechanism and likely disease factor in cancer

Researchers at the University of Illinois Urbana-Champaign and Stanford University School of Medicine have identified a link between RNA polymerase III subunit composition and transcription, an advancement that has potential implications for future cancer research. Their findings were published in...

Researchers find new control mechanism for sugar metabolism in gut microbes

In a new University of Illinois study, researchers found that genes encoding a previously unstudied family of RBPs are highly expressed in many Bacteroides species. They also demonstrated that mutants of the prevalent human gut bacteria Bacteroides thetaiotaomicron that lacked RBPs exhibited...

Welcome to Professor Asma Hatoum

Professor Hatoum was one of ten new faculty hires made in the School of Molecular and Cellular Biology in the last three years. Hatoum is an assistant professor of microbiology and is part of the Microbial Systems Initiative.

Researchers uncover the role of a noncoding RNA in cell proliferation

Kannanganattu V. Prasanth, professor of cell and developmental biology, and members of his lab investigate the regulation of gene expression and RNA biology with a focus on cancer. In a new article published in eLife, “The S-phase-induced lncRNA promotes cell proliferation by controlling YAP1/Hippo...

Vanderpool Lab: Small RNAs fine tune how bacteria change their membranes to resist environmental stress

Graduate student Colleen Bianco and Professor Carin Vanderpool spearheaded a study that centered on how E. coli and Salmonella bacteria use RNA-based regulatory mechanisms to modify their membrane lipids in response to different stimuli. Their findings, with collaborator Kathrin Frölich (Ludwig...

Mutations in noncoding genes could play big role in regulating cancer, study finds

Professor Kannanganattu Prasanth led a team that found that certain genes that don’t code for proteins could play an important regulatory role in breast cancer.

Salmonella’s Sweet Spot

MCB Collaboration Unravels Bacteria’s Virulence Regulation System