K.V. Prasanth lab discovers cancer connections with MALAT1

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Prasanth’s lab published several papers on a particular lncRNA called MALAT1, with significant findings showing an important link between cancer and MALAT1. They found that when MALAT1 is overexpressed in breast cells, the cells form tumors. Conversely, when it is depleted in breast cancer cells,...

RNA-Binding protein, Mov10, is key to both survival and brain function

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A study led by Dr. Geena Skariah, a recent Neuroscience graduate of the Ceman lab in Cell and Developmental Biology, and current postdoctoral researcher at the University of Michigan, revealed the importance of the protein Mov10 (Moloney leukemia virus 10) in neurological development in animals....

A new RNA repair complex employing a “one-stop shopping” repair mechanism

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Biochemistry graduate student Pei Wang and Associate Professor Raven Huang have discovered a new bacterial RNA repair complex. The structure of the 270-kDa RNA repair complex revealed that it is built like a shopping mall, and RNA repair can be achieved having the damaged RNA visiting four active...