University of Illinois researcher Erik Nelson and members of his lab have made an important discovery about the relationship between cholesterol and breast cancer progression with crucial implications for breast cancer therapeutics....
A naturally occurring protein that tends to be expressed at higher levels in breast cancer cells boosts the effectiveness of some anticancer agents, including doxorubicin, one of the most widely used chemotherapies, and a preclinical drug known as ErSO, researchers report. The protein, FGD3,...
As a graduate student in the Erik Nelson Lab, Dhanya Pradeep investigates how metabolic signaling pathways regulate immune responses in breast cancer. Her research is centered on the farnesoid X receptor (FXR), a metabolic receptor...
Researchers at the University of Illinois Urbana-Champaign will develop a radically new platform to manufacture tumor models and expand their availability for medical research and personalized medicine, thanks to a $21 million grant from the Advanced Research Projects...
For typical illnesses, the body’s immune system is a robust, pathogen-killing machine. It provides a general defense against harmful germs while also adapting and producing antibodies that target specific bacteria or viruses. After fighting off an infection like the flu, the body produces...
An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer.
Their findings, published in Breast Cancer Research and Treatment,...
Estrogen receptor-positive breast cancer is the most common form of breast cancer, affecting approximately 75 percent of breast cancer patients. In advanced and metastatic form, it is lethal, claiming the lives of nearly 350,000 individuals annually. Presently, no drug is able to eradicate these...
Scientists have identified a protein that plays a pivotal role in the action of several emerging cancer therapies. The researchers say the discovery will likely aid efforts to fine-tune the use of immunotherapies against several challenging cancers.
University of Illinois scientists Benita Katzenellenbogen, Swanlund Professor of Molecular & Integrative Physiology, and John Katzenellenbogen, Swanlund Professor of Chemistry, have developed a new compound with efficacy in suppressing tumor initiation, progression, and metastasis of...
The Beckman Institute has announced its 2023 class of six postdoctoral fellows. Fellows are selected in accordance with the core values of the institute: excellence, collaboration, integrity, transdisciplinarity, exploration, and diversity.
