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Research

News about research advances, awards, and more.

RNA binding protein implicated in brain development, fear memory

Researchers from the University of Illinois have identified an RNA binding protein called MOV10 as a critical factor in memory formation and learning. Their findings, published this month in BMC Biology, will...

New study sheds light on liver maturation, specialization

Researchers from the University of Illinois have identified a key process coordinating liver maturation and polyploidization, a state in which cells carry more than two sets of chromosomes. Their findings, published in Genes and Development,...

Meet MCB: Dr. Sayee Anakk’s research journey

Dr. Sayeepriyadarshini “Sayee” Anakk is newly promoted professor of molecular and integrative physiology whose research program focuses on understanding liver metabolism in normal and diseased states...

MCB researchers investigate ways to weaponize bacterial viruses to combat superbugs

Researchers from the University of Illinois have reported complementary discoveries that will improve scientists’ understanding of immune systems in bacteria and equip clinicians with more effective options for treating antibiotic-resistant infections. Antibiotic-resistant bacteria known as...

Can bacteria handle stress? Study reveals how combined stressors overwhelm harmful bacteria

The human body is a stressful place for bacteria to live. They must defend against many chemical and physical stressors, in addition to the immune system. One major physical stressor is fluid flow, which constantly circulates in the bloodstream, urinary tract, and lungs. Research has...

Illuminating signal transduction mechanisms in Cys-loop receptors

Researchers from the University of Illinois have discovered a key factor responsible for facilitating signal transduction in Cys-loop receptors, providing insight into a longstanding question in the field of ion-channel physiology and contributing to rational drug design. Their findings appear in...

Gut microbiome research sheds light on oligosaccharide breakdown, prebiotics

The human gut is a diverse and densely populated environment filled with bacteria and other microbes in fierce competition for resources. One major colonizer in the human colon is Bacteroides, a genus of bacteria that can break down a wide variety of complex carbohydrates indigestible by...

Asking “Big questions”: UI researchers illuminate on transcriptional interplay among RNA polymerase enzymes

Investigators from the University of Illinois have created a whole-genome map that charts the occupancies of RNA polymerase enzymes in humans, discovering unexpected patterns in the process. Their findings appear in ...

New campuswide project will develop rapid manufacturing of tumor models

Researchers at the University of Illinois Urbana-Champaign will develop a radically new platform to manufacture tumor models and expand their availability for medical research and personalized medicine, thanks to a $21 million grant from the Advanced Research Projects...

Team discovers naturally occurring DNA-protein hybrids

Thanks to a serendipitous discovery and a lot of painstaking work, scientists can now build biohybrid molecules that combine the homing powers of DNA with the broad functional repertoire of proteins — without having to synthesize them one by one, researchers report in a new study. Using a naturally...