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Molecular & Integrative Physiology (MIP)

New drug compounds show promise against endometriosis

An interdisciplinary research team, including molecular and integrative physiology professors Benita Katzenellenbogen and Milan Bagchi, has developed a new approach to treating endometriosis. Their research appears in Science Translational Medicine.

Jongsook Kim Kemper’s lab discovers that elevated acetylation of FXR in obesity promotes hepatic inflammation, published in the EMBO Journal

Associate Professor of Molecular and Integrative Physiology, Jongsook Kim Kemper, post-doctoral researcher, Dong-Hyun Kim, and their colleagues discovered that the function of a key metabolic transcriptional regulator, FXR, is modulated by an acetyl/SUMO switch, which is dysregulated in obesity....

Professor Jongsook Kim Kemper and collaborators discover FXR and CREB as key physiological regulators of autophagy, published in the journal Nature.

Autophagy or “self-eating” is the breakdown and recycling of cellular components and is essential for cellular survival under starvation but must be suppressed upon feeding. Acute regulation of preexisting autophagy machinery by protein phosphorylation is well defined, but longer-term regulation...

NSF awards BRAIN EAGER grant to team led by Martha Gillette

A Team led by Martha Gillette, professor of Cell and Developmental Biology, Molecular and Integrative Physiology, Neuroscience and Bioengineering, has been awarded a BRAIN EAGER grant from NSF for a project titled “Multiscale dynamics and emergent properties of suprachiasmatic circuits in real time...

Dr. Claudio Grosman named Romano Professorial Scholar

Dr. Claudio Grosman has been named a Richard and Margaret Romano Professorial Scholar. The three-year appointment recognizes outstanding research achievement and campus leadership through the College of Liberal Arts and Sciences.

In Memoriam: Colin A. Wraight

Professor Colin A. Wraight passed away July 10, 2014 at the age of 68 after a long and heroic struggle with cancer. Professor Wraight employed biochemical and biophysical methods to understand how the structure of membrane proteins allowed them to catalyze the transfer of electrons and protons...

Side-chain rotamers make a difference

Third-year Biophysics graduate student Tyler Harpole and Professor of Molecular and Integrative Physiology, Biophysics and Neuroscience, Claudio Grosman, have used molecular dynamics and Brownian dynamics computer simulations to test a novel hypothesis as to how the nicotinic acetylcholine receptor...

Assistant Professor of MIP Sayee Anakk Publishes New Study in Cell Reports

Assistant Professor of Molecular and Integrative Physiology Sayeepriyadarshini Anakk published an article in the November 21, 2013, edition of Cell Reports entitled "Bile Acids Activate YAP to Promote Liver Carcinogenesis."

College of Medicine Recognizes Byron Kemper, Abigail Salyers for Excellence

The College of Medicine at Illinois recognized Emeritus Professor of Molecular and Integrative Physiology Byron Kemper and Arends Professor Emerita of Microbiology Abigail A. Salyers for their excellence in research and teaching.

Daniel Llano Selected as Pew Scholars Nominee

Congratulations to Assistant Professor of Molecular and Integrative Physiology and the College of Medicine, and Carle Foundation Hospital neurologist Daniel Llano, who has been selected as the Urbana campus nominee for the 2014 Pew Scholars Program in the Biomedical Sciences.