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Alzheimer's disease

Researchers funded to develop ultrasound imaging tools to study Alzheimer's disease

Interdisciplinary researchers at the Beckman Institute, including Molecular & Integrative Physiology Professor Dan Llano, received federal funding to develop ultrasound imaging methods for studying the neurovascular changes underlying Alzheimer's disease. Their low-cost, widely accessible...

New ultrasound tool measures blood flow, images microvasculature in the brain

Researchers at the Beckman Institute developed a technique for producing super-resolution ultrasound images of tissue microvasculature in just a fraction of the time previously needed. Their work could enable future research into the neurovascular mechanisms behind conditions like Alzheimer’s...

Research illuminates balancing act for protein linked to Fragile X Syndrome and Alzheimer's disease

A new study by researchers at the University of Illinois Urbana-Champaign suggests the overexpression of a particular gene could serve as a risk factor for Alzheimer’s disease. Their findings could also lead to better understandings of the links between Alzheimer’s disease, Fragile X Syndrome, and...

Carle Illinois research reveals new insight into links between Alzheimer's Disease and hearing loss

Researchers at Carle Illinois College of Medicine have uncovered new evidence about hearing loss in patients with Alzheimer’s Disease (AD). It pinpoints unexpected areas of brain shrinkage in AD patients with hearing loss. The work could eventually lead to earlier intervention and new treatment...

Meet MCB: Professor Nien-Pei Tsai

Dr. Tsai’s lab focuses on understanding the molecular mechanisms underlying neuronal excitability imbalance in neurological and psychiatric disorders including epilepsy and autism.

Meet MCB: Professor Dan Llano

Professor Daniel Llano is a neurologist at the Carle Neuroscience Institute and has been a faculty member in the MIP department since 2010. He obtained his BS, PhD, and MD at UIUC before moving to Massachusetts to pursue his clinical training at Harvard Medical School. He later became a post-...

Neuronal Excitability in Health and Disease

A new era has dawned in understanding neuropathological disorders such as epilepsy, schizophrenia, depression, and autism spectrum disorders. These disorders, traditionally classified in the Diagnostic and Statistical Manual of Mental Disorders by the American Psychiatric Society, are now being re-...

Synaptic Membrane Nanodiscs May Help Find Alzheimer’s Disease Therapeutics

Congratulations to Stephen Sligar for his recent publication in PLoS One: “Nanoscale Synaptic Membrane Mimetic Allows Unbiased High Throughput Screen that Targets Binding Sites for Alzheimer’s-Associated Aβ Oligomers.” Using a High Throughput Screening (HTS) facility at NU, Sligar and colleagues...

MCB Director's Seminar

On November 18 at this year's MCB Director's Seminar, special guest Northwestern University Professor of Neurobiology William L. Klein delivered the talk: "Synaptotoxic AΒ Oligomers (ADDLs): A Molecular Basis for the Cause, Diagnosis and Treatment of Alzheimer's Disease."