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Fragile X Syndrome

New study uncovers novel receptor function in Fragile X syndrome

Fragile X syndrome is one of the most commonly inherited forms of autism and intellectual disability, and no treatment currently exists. But a team of University of Illinois researchers led by Vipendra Kumar, a postdoctoral researcher in the Department of Molecular & Integrative Physiology, has...

Meet MCB: Postdoc Vipendra Kumar

In recognition of his work, Dr. Vipendra Kumar was recently awarded a fellowship from the FRAXA Research Foundation, whose mission is to discover better treatments and ultimately cure the genetic disorder Fragile X Syndrome.

Research illuminates balancing act for protein linked to Fragile X Syndrome and Alzheimer's disease

A new study by researchers at the University of Illinois Urbana-Champaign suggests the overexpression of a particular gene could serve as a risk factor for Alzheimer’s disease. Their findings could also lead to better understandings of the links between Alzheimer’s disease, Fragile X Syndrome, and...

Meet MCB: Temirlan Shilikbay, cell & developmental biology PhD student

The School of MCB is proud to highlight our graduate students, including Temirlan Shilikbay, now in his third year at the University of Illinois Urbana-Champaign. He is a PhD candidate in professor Stephanie Ceman's lab in the Department of Cell and Developmental Biology. The lab's goal is to study...

Meet MCB: Professor Nien-Pei Tsai

Dr. Tsai’s lab focuses on understanding the molecular mechanisms underlying neuronal excitability imbalance in neurological and psychiatric disorders including epilepsy and autism.

Study: Protein found to be key component in irregularly excited brain cells

Research scientist Kwan Young Lee, molecular and integrative physiology professor Nien-Pei Tsai, and their colleagues discovered that an overabundance of the tumor suppressor protein p53 in neurons can lead to impaired regulation of neuronal excitability in a mouse model of Fragile X syndrome.

Neuronal Excitability in Health and Disease

A new era has dawned in understanding neuropathological disorders such as epilepsy, schizophrenia, depression, and autism spectrum disorders. These disorders, traditionally classified in the Diagnostic and Statistical Manual of Mental Disorders by the American Psychiatric Society, are now being re-...

Technological Breakthroughs Transform Biological Inquiry in Neuroscience

The infinitely complex workings of the human brain have intrigued researchers for centuries. Our understanding of its workings have been limited, not by our curiosity, but by our tools. Now, with the growth of new molecular biology and genomics approaches, big data, and engineering advances that...

Ceman lab in Cell Reports: How FMRP interacts with RNA helicase MOV10 to regulate translation

The Ceman laboratory, with lead authors Phil Kenny and Miri Kim, have shown that FMRP is able to facilitate or suppress the translation of a subset of its target mRNAs by its interaction with the RNA helicase MOV10.

William T. Greenough, an early explorer of brain plasticity, dies at 69

William T. Greenough, a professor emeritus of psychology, was a pioneer in studies of brain development, the neural basis of learning and memory, and the effects of aging, exercise, injury and environmental enrichment on the brain.