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Computational Biology

Study: Brain circuits for locomotion evolved long before appendages and skeletons

A new study finds parallels between the brain architecture that drives locomotion in sea slugs and that of more complex segmented creatures with jointed skeletons and appendages. 

Meet MCB: Biochemistry PhD student Yiquan Wang

Yiquan Wang is a PhD student in the School of Molecular and Cellular Biology at UIUC. In our latest "Meet MCB" video, Yiquan shares how he's bridging his love for art and biochemistry to help people better understand virology.

COVID-19 virus spike protein flexibility improved by human cell's own modifications

When the coronavirus causing COVID-19 infects human cells, the cell’s protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect other cells and to evade antibodies, a new study from the University of...

The Changing Shape of HIV

The Procko lab applies big data tools to molecular biochemistry.Their goal: a better understanding of how we might fight HIV-1.

Decoding Life with MCB: Decoy Proteins

Life is extraordinary. So is the work we do. In a brand new podcast, Decoding Life with MCB, the School of Molecular and Cellular Biology at the University of Illinois Urbana-Champaign explores the impact of our students, faculty, staff, and alumni in each episode.

Carle Illinois research reveals new insight into links between Alzheimer's Disease and hearing loss

Researchers at Carle Illinois College of Medicine have uncovered new evidence about hearing loss in patients with Alzheimer’s Disease (AD). It pinpoints unexpected areas of brain shrinkage in AD patients with hearing loss. The work could eventually lead to earlier intervention and new treatment...

Geographies of death: Study maps COVID-19 health disparities in Greater Santiago

People up to age 40 living in economically depressed municipalities in the Greater Santiago, Chile, metropolitan area were three times more likely to die as a result of the infection than their counterparts in wealthier areas, researchers report in the journal Science. People ages 41-80 in low...

What is the new variant of coronavirus in the UK?

New mutations to the coronavirus that causes COVID-19 are emerging, including one in the United Kingdom with higher infection rates that has sparked new travel bans. Erik Procko, a professor of biochemistry at the University of Illinois Urbana-Champaign, has been studying mutations in the spike...

Decoy receptor neutralizes coronavirus in cell cultures

As the COVID-19 pandemic continues to spread, scientists and health care providers are seeking ways to keep the coronavirus from infecting tissues once they’re exposed. A new study suggests luring the virus with a decoy – an engineered, free-floating receptor protein – that binds the virus and...

Simulated sea slug gets addicted to drug

Rhanor Gillette and his colleagues simulated a sea slug brain in a computer model, added a few extra circuits, and gave it access to food and an intoxicating drug. The work offers insight into the process of addiction and will be a useful tool for further studies, Gillette said.