Congratulations to Professor Catherine Christian-Hinman, who was selected to receive the 2023 University of Virginia School of Medicine Distinguished Achievement Award in Biomedical Sciences. The award recognizes exceptional research and professional accomplishments, outstanding discovery and...
A new study from the University of Illinois further helps explain links between epilepsy and reproductive comorbidities. The Christian-Hinman laboratory's findings were published in the journal Neurobiology of Disease.
Patients with temporal lobe epilepsy, the most common form of focal epilepsy, often have seizures that start from one side of the hippocampus and not the other. Such patients may also experience complications such as cognitive impairment and reproductive endocrine disruption. Although it’s been...
Researchers studying epileptic seizures of the temporal lobe – the most common type of epilepsy – discovered a compound that reduces seizures in the hippocampus, a brain region where many such seizures originate. The compound, known as TC-2153, lessened the severity of seizures in mice. The...
Mice with a genetic mutation that’s been observed in patients with epileptic encephalopathy, a severe form of congenital epilepsy, exhibit not only the seizure, developmental and behavioral symptoms of the disorder, but also neural degeneration and inflammation in the brain, University of Illinois...
Researchers at the University of Illinois Urbana-Champaign are hopeful their findings on the gating mechanisms behind epilepsy-associated potassium channels could provide a foundation for new therapeutic strategies for treating epilepsy, especially in young patients. Their research was recently...
Recent research from Professor Catherine Christian-Hinman in the Department of Molecular and Integrative Physiology has identified an animal model capable of modeling some aspects of catamenial epilepsy without hormone treatments, creating exciting possibilities in the field for advancement in...
A new study uses magnetic resonance elastography to compare the stiffness of the hippocampus in patients who have epilepsy with healthy individuals. The technique can improve the detection and characterization of the disease.
The lab of Hee Jung Chung, Associate Professor in the Department of Molecular and Integrative Physiology, recently released a paper in Scientific Reports titled “Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy” to help fill in the gaps in our...