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Imaging

Members of MCB labs earn newly-established fellowships focused on cancer research

The Beckman Institute has announced its 2023 class of six postdoctoral fellows. Fellows are selected in accordance with the core values of the institute: excellence, collaboration, integrity, transdisciplinarity, exploration, and diversity.

A different kind of cell signal: New method enables clear, precise imaging of human cells

Researchers at the Beckman Institute for Advanced Science and Technology have developed an innovative way to ‘see’ the fine structure and chemical composition of a human cell with unmatched clarity and precision. Their technique, which appeared in PNAS earlier this week, takes a creative — and...

Carle Illinois research reveals new insight into links between Alzheimer's Disease and hearing loss

Researchers at Carle Illinois College of Medicine have uncovered new evidence about hearing loss in patients with Alzheimer’s Disease (AD). It pinpoints unexpected areas of brain shrinkage in AD patients with hearing loss. The work could eventually lead to earlier intervention and new treatment...

Light can trigger key signaling pathway for embryonic development, cancer

Blue light is illuminating new understanding of a key signaling pathway in embryo development, tissue maintenance, and cancer genesis.

Kai Zhang receives 2021 Scialog Collaborative Innovation Award to study the gut-brain axis

Congratulations to Kai Zhang, professor of biochemistry, whose team was selected for a 2021 Scialog Collaborative Innovation Award. The project is entitled, “Engineering Enteric Neuron Activity to Enhance Antimicrobial Immunity in the Gut.”

Belmont Lab offers new insights on nuclear speckles, improved mapping method

In a new publication, University of Illinois PhD graduate Liguo Zhang of the Belmont laboratory and colleagues introduce an improved version of TSA-seq and use it to demonstrate how changes in gene association with nuclear speckles correlate with changes in gene expression.

New optogenetics study shows promising results for neuronal regeneration

New research by biochemistry professor Kai Zhang and his team at the University of Illinois uses the groundbreaking field of optogenetics to show a potential new route for controlling specific neuron growth with incredible accuracy. Their recent paper “Optical control of ERK and AKT signaling...

Tyramide signal amplification mass spectrometry (TSA-MS) ratio identifies nuclear speckle proteins

Proximity labeling of cell structures followed by mass spectrometry has become an increasingly popular proteomics approach to identify what proteins localize to different cell structures. In practice, however, results are typically confusing, with long lists of hundreds of proteins identified,...

Nuclear speckle contact amplifies gene expression

Recent work from the Laboratory in Cell and Developmental Biology was featured in the Journal of Cell Biology.

Multiscale imaging shines light on the unique importance of bone marrow during HIV infection

HIV-1 affects and kills millions of people globally, but not enough information exists regarding the types of cells that HIV-1 targets in different tissues or the virus’s mechanism of spreading throughout the body. Viruses often ride the body’s circulatory systems to scatter throughout an organism...